A Multi-Disciplinary Approach

The care of patients with Liver, Pancreas and Bile Duct disease requires multiple disciplines. To make sure our patients have the best outcomes, each patient's case is discussed among our team of dedicated physicians at weekly conferences. Our team includes a Liver, Pancreas and Biliary Surgery, Hepatology, Interventional Endoscopy, Interventional Radiology, Gastroenterology, Medical Oncology, Radiation Oncology, and an expert Radiologist in body imaging.

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Dr. de la Torre is Director of Liver, Pancreas and Biliary Surgery at St. Joseph's Medical Center. He is also Adjunct Associate Professor of Surgery at Rutgers University, Newark Campus.

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Medical Doctorate
Johns Hopkins School of Medicine
Baltimore, Maryland
Class of 1989

B.A. Chemistry
Queens College, City University of New York
Flushing, New York
Class of 1984

Visiting Scholar Training Program
Division of Liver Transplant and Hepatobiliary Surgery
(Live Donor Liver Transplant Training)
Asan Medical Center
Seoul, South Korea
March 9-20, 2015

Liver Transplant Fellowship
New Jersey Medical School
University Hospital, University of Medicine & Dentistry of New Jersey
Newark, New Jersey
1999-2000

Kidney and Pancreas Transplant Fellowship
University of Maryland Medical Systems
Baltimore, Maryland
1995-1998

General Surgery Residency
New Jersey Medical School
University Hospital, University of Medicine & Dentistry of New Jersey
Newark, New Jersey
1990-1995
American Board of Surgery 1999, Recertified 2009
Fellow of the American College of Surgeons 2012
33. Use of sorafenib preceeding hepatic artery chemo-embolizaton in patients with hepatocellular cancer. de la Torre AD, Castaneda I, Contractor, Clyde D, Kisza P, Gonzalez S

32. A Phase I trial on a multimodality regimen to reduce tumor tolerance and induce anti-tumor immunity: Use of low dose cyclophosphaminde followed by low dose tumoral radiation, intra-tumoral injection of the toll-like-receptor III agonist Polyinosinic-Polycytidylic acid stabilized with polylysine and carboxymethylcellulose (poly-ICLC) combined with hepatic artery embolization, followed by systemic immune boosting with intramuscular poly-ICLC. de la Torre AD, Castaneda I, Contractor s, Cathgard C, Razdan D, Clyde D, Kisza P, Gonzalez S, Garcia T, Korogodsky M, Salazar A (in preparation)

31. The role of Endo-GIA stapler devices in minimally invasive hepatic parenchymal resection for liver tumors de la Torre AN (in preparation)

30. Lasfar A, Abushahba W, Castaneda I, Tsou W, Yuan Y, Raveche E, Reuhl K, de la Torre AN, Kotenko SV. Combination of IFN-α and IFN-λ induce complete remission in BNL hepatoma model: Relevance of IFN-α/λ cross- talk and host immunomodulation (submitted)

29. Castaneda I, Ekholy N, Tham N, Herrera IB, Beaty P, Johnson MB, Cynthia Paige , Malapero RJ, Leevy CB, de la Torre AN. Use of Patient Targeted Informatics to Survey Patient Risk for Chronic Viral Hepatitis C and B and Guide Targeted Blood Testing (submitted)

28. Muir AJ, Shiffman ML, Zaman A, Yoffe B, de la Torre A, Flamm S, Gordon S, Marotta P, Vierling J, Lopez-Talavera JC, Byrnes-Blake K, Fontana D, Freeman J, Gray T, Hausman D, Hunder NN, Lawitz E. Phase 1b Dose- Ranging Study of PEG-Interferon-Lambda Plus Ribavirin in Patients with Chronic Genotype 1 Hepatitis C Virus Infection. Hepatology. 2010 May 14

27. Abushahba W, Lasfar A , Balan M, Castaneda I, Yuan Y, Prescott L, Reuhl K, Raveche E, de la Torre AN, Kotenko SV. Antitumor Activity of Type I and Type III Interferons in BNL Hepatoma Model. Cancer Immunol Immunother. 2010 Mar 9

26. Ferrante JM, Winston DG, Chen PH, de la Torre AD Family Physicians’ Knowledge and Practices Regarding Chronic Hepatitis and Monitoring for Liver Cancer. Family Medicine Family Medicine 2008 May: 40(5), 345-351

25. Koneru B, Shareef A, Dikdan G, Desai K, Klein KM, Peng B, Wachsberg RH, de la Torre AN, Debroy M, Fisher A, Wilson DJ, Samanta AK. The ischemic preconditioningparadox in deceased donor liver transplantation- evidence from a prospectiverandomized single blind clinical trial. Am J Transplant. 2007 Dec;7(12):2788-96.

24. Abujudeh H, Contractor D, delaTorre A, Koneru B. Rescue TIPS in acute Budd-Chiari syndrome. AJR Am J Roentgenol. 2005 Jul;185(1):89-91.

23. Ponnudurai RN, Koneru B, Akhtar SA, Wachsberg RH, Fisher A, Wilson DJ, de la Torre AN. Vasopressor administration during liver transplant surgery and its effect on endotracheal reintubation rate in the postoperative period: a prospective, randomized, double-blind, placebo-controlled trial. Clin Ther. 2005 Feb;27(2):192-8.

22. Koneru B, Fisher A, He Y, Klein KM, Skurnick J, Wilson DJ, de la Torre AN, Merchant A, Arora R, Samanta AK. Ischemic preconditioning in deceased donor liver transplantation: a prospective randomized clinical trial of safety and efficacy. Liver Transpl. 2005 Feb;11(2):196-202.

21. Harrison LE, Reichman T, Koneru B, Fisher A, Wilson D, dela Torre A, Samanta A, Korogodsky M. Racial discrepancies in the outcome of patients with hepatocellular carcinoma. Arch Surg. 2004 Sep;139(9):992-6.

20. de la Torre AN, Fisher A, Wilson DJ, Reitsma W, Goerlitz F, Koneru. Minimally Invasive Optimization of Organ Donor Resuscitation: Case Reports. Prog Transplant. 2005 Mar;15(1):27-32.

19. Fisher A, Seguel JM, de la Torre AN, Wilson D, Merchant A, Arora RK, Koneru B. Effect of sirolimus on infection incidence in liver transplant recipients. Liver Transpl. 2004 Feb;10(2):193-8.

18. Dikdan, GS, Saba SC, de la Torre AD, Roth JR, Wang S, Koneru B. Role of Oxidative Stress in the Increased Activation of Signal Transducers and Activators of Transcription-3 in the Fatty Livers of Obese Zucker Rats. Surgery 2004 136(3):677

17. de la Torre AN, Fisher A, Wilson DJ, Harrison J, Koneru B. A Case Report of Donor to Recipient Transmission of Severe Thrombocytopenia Purpura. Transplantation. 2004 May 15;77(9):1473-4

16. Harrison LE, Koneru B, Baramipour P, Fisher A, Barone A, Wilson D, dela Torre AN, Cho KC, Contractor D, Korogodsky M. Locoregional recurrences are frequent after radiofrequency ablation for Hepatocellular carcinoma. J Am Coll Surg J Am Coll Surg. 2003 Nov; 197(5): 759-64.

15. Monteiro I, McLoughlin LM, Fisher A, dela Torre AN, Koneru B. Rituximab with plasmapheresis and splenectomy in ABO-Incompatible liver transplantation. Transplantation 2003; 76(11):1648


14. Das K, Fisher A, Wilson DJ, dela Torre AN, Seguel J, Koneru B. Primary non-Hodgkin’s lymphoma of the bile ducts mimicking cholangiocarcinoma: Report of two cases and review of the literature. Surgery 2003 Sep; 134(3):496


13. Wilson DJ, Fisher A, Das K, Goerlitz F, Holland BK, de la Torre AN, Merchant A, Seguel J, Samanta AK, Koneru B.. Donors with cardiac arrest: Improved organ recovery but no preconditioning benefit in liver allografts. Transplantation 2003; 75:1683-1687.


12. Koneru B, Fisher A, Wilson DJ, Klein KM, de la Torre AN, Seguel J. De novo pulmonary hypertension following successful liver transplantation. Am J Transplant. 2002 Oct;2(9):883-6.


11. delaTorre A.N., Schroeder R.A., Punzulan C., Kuo P.C.: Endotoxin-mediated S-nitrosylation of p50 alters nf-kappa B-dependent gene transcription in ANA-1 murine macrophages. Journal of Immunology 1999; 162(7): 4101. 1999.


10. delaTorre A.N., Schroeder R.A., Bartlett S.T., Kuo P.C.: Differential Effects of Nitric Oxide-mediated S-nitrosylation on p50 and c-jun DNA Binding. Surgery. 1998; 124(2):137.


9. Kuo P.C., Drachenberg C.I., delaTorre A.N., Bartlett S.T., Lim J.W., Plotkin J.S., Johnson L.B.: Apoptosis and Hepatic Allograft Reperfusion Injury. Clinical Transplantation. 1997; 12(3):219.

8. delaTorre A.N., Schroeder R.A., Kuo P.C.: Alteration of NF-kappa B p50 Binding Kinetics by S-Nitrosylation. Biophysical Bioresearch Communications. 1997; 238(3):703.

7. Bartlett S.T., Schweitzer E.J., Kuo P.C., Johnson L.B., delaTorre A.N., Hadley G.A.: Prevention of Autoimmune Islet Allograft Destruction by Engraftment of Donor T Cells. Transplantation 1997; 63(2):299.

6. Schroeder R.A., delaTorre A.N., Kuo P.C.: A CD14 Dependent Mechanism For Endotoxin-Mediated Nitric Oxide Synthesis In Murine Macrophages. American Journal of Physiology 1997; 273(1):C1030.

5. Bartlett S.T., delaTorre A.N., Johnson L.B., Kuo P.C., Schweitzer E.J.: Long-Term Pancreatic Function: Potential Benefits. Transplantation Proceedings 1997; 28(4):2128.

4. Johnson L.B., Kuo P.C., Schweitzer E.J., Ratner L.E., Klassen D.K., Hoehn-Saric E.W., delaTorre A.N., Weir M.R., Strange J., Bartlett S.T: Double Renal Allografts Successfully Increase Utilization of Kidneys from Older Donors Within a Single Organ Procurement Organization. Transplantation 1997; 62(11):1581.

3. Kuo P.C., delaTorre A.N., Johnson, L.B., Schweitzer, E.J., Bartlett, S.T.: Bilateral Retroperitoneal Renal Allografts: Technique for Placement Through a Midline Incision. Journal of the American College of Surgeons 1997; 183(5):529.

2. delaTorre A.N., Kuo P.C., Plotkin J.S., Ridge L.A., Howell C.D., Bartlett S.T., Johnson L.B.: Influence of Donor Base Deficit Status on Recipient Outcomes in Liver Transplantation. Transplantation Proceeding 1997; 29(1-2):474.

1. Koneru B, Reddy M.C., delaTorre, A.N., Patel P, Ippolito T, Ferrante R.J.: Studies of Hepatic Warm Ischemia in the Obese Zucker Rat. Transplantation 1995; 59(7):942.
Immuno-modulatory strategies to auto-vaccinate patients against primary and metastatic cancers of the liver; sequence and timing determination of irradiation, an immune adjuvant (Poly I:C LC) and tumor ablation to generate robust anti-tumor immune responsiveness. Phase I/II clinical Trial.
NJMS/UMDNJ IRB 0120070076, FDA IND 43,984, clinical trial.gov NCT00553683, Sponsor Oncovir Biopharm

Minimization of social intrusion with audio-computer assisted survey interviewing (audio-CASI) to increase reporting of risk factors that warrant blood testing for chronic viral hepatitis and high-risk populations for liver cancer.
NJMS/UMDNJ IRB 0120080130

Phase II Pilot Study of Sorafenib Tosylate Before and After Hepatic Arterial Chemoembolization With Doxorubicin Hydrochloride and Mitomycin C in Patients With Localized Unresectable Hepatocellular Carcinoma.
NJMS/UMDNJ IRB 20090859, BAYER-IST000477, NCT00949182

A Multicenter, Randomized, Double-Blind, Phase 3 Study of Ramucirumab (IMC-1121B) Drug Product and Best Supportive Care (BSC) Versus Placebo and BSC as Second-Line Treatment in Patients With Hepatocellular Carcinoma Following First-Line Therapy With Sorafenib
NCT01140347

Randomized, Controlled Phase 2a/b Study of the Efficacy and Safety of PEGIL-29 Administered in Combination with Ribavirin to Treatment-Naive Subjects with Chronic Hepatitis C Virus Infection.
FDA IND 100,420, WIRB® Protocol 20091710, Sponsor Zymogenetics Pharmaceutical

Characterization of focal liver lesions with SonoVue®-enhanced ultrasound imaging: a phase III, intrapatient comparative study versus unenhanced ultrasound imaging using histology or combined imaging/clinical data as truth standard
FDA IND: 46,958, WIRB® 20101498, NCT00829413, Sponsor Bracco Pharmaceutical

Comparative role of type I and type III interferons in the pathogenesis of hepatocellular carcinoma. IRB approved study to assess hepatic intra-tumor, peri-tumor and non-tumor environment responses to interferons and relation to development of hepatocellular cancer.
NJMS/UMDNJ IRB 0120060207


Healthcare Foundation of New Jersey
Principle Investigator 2007
A Clinical Approach to Understand the Underdiagnosis and Treatment of Hepatitis C and B

Roche Pharmaceutical
Principle Investigator 2007
Use of Audio-Computer Assisted Survey interview to Engage People in Need of Chronic Viral Hepatitis Blood Testing

Bayer Pharmaceutical
Principle Investigator 2009
Phase II Pilot Study of Sorafenib Tosylate Before and After Hepatic Arterial Chemoembolization With Doxorubicin Hydrochloride and Mitomycin C in Patients With Localized Unresectable Hepatocellular Carcinoma

Gilead Pharmaceutical
Principle Investigator 2009
A Clinical Approach to Understand Obstacles To the Diagnosis of Chronic Viral Hepatitis in Order to Improve Early Diagnosis of Liver Cancer

Human Services and Resources Administration 08-130:
Principle Investigator 2009
Patient Navigation to Increase Access to Chronic Viral Hepatitis Treatment and Liver Cancer Screening in Low Income Urban Communities Subject to Health Disparities

Healthcare Foundation of New Jersey
Principle Investigator: 2010
Support and Optimization of Infrastructure to Reduce Liver Disease Mortality

Medical Advisor Latino Organization for Liver Awareness 2004-2010

Vice Medical Director New Jersey Tissue and Organ Sharing Network 2005-2010

New Jersey State DOH Chronic Viral Hepatitis Advisory Board 2006-present

Board of Directors: New Jersey Tissue and Organ Sharing Network 2007-2010

Vice-Chairman: New Jersey Hep-Help Alliance: October 2008-present



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HepatoPancreatoBiliary Advanced Practice Nurse
ph: 973-754-2786
fx: 973-754-3528
Patient Coordinator, scheduling and authorizations
ph: 973-754-2315
fx: 973-754-3528
Research Coordinator
ph: 973-972-6812
fx: 862 902-1669

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Director of Hepatology

Dr Maliha Ahmad is a Transplant Hepatologist with 7 years experience at the Rutger's Newark Liver Transplant program. Working at the busiest liver transplant program in New Jersey, she has taken care of thousands of patients with all types of liver disease. She has been a co-investigator on numerous clinical trials.
Hepatology Physician Assistant

Ms Korogodsky worked 10 years in adult liver transplant at the Rutgers Newark Program and 2 years in pediatric liver transplant at Columbia Presbyterian Medical Center.
Medical Assistant
Patient Navigator

Farhan Ayoub oversees our automated EMR order entry program to test all patients born between 1945-1965, "Baby Boomers", with the St Joseph's Health Care System.

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Edward Milman M.D.
Section Chief Diagnostic and Interventional Musculoskeletal Radiology
Director of MRI St Joseph's Hospital Medical Center.

Dr. Milman completed his Medical School education at SUNY Downstate, Brooklyn NY. He continued his training in Radiology as a resident at New York Presbyterian Hospital of Columbia University in New York. He stayed at Columbia University to receive subspecialty training during his Fellowship in Musculoskeletal/Body MRI. Dr. Milman specializes in Hepatobiliary/Musculoskeletal/Body Cross sectional imaging and has special interest and expertise in Cardiac CTA and MRI imaging. He received prestigious "Teacher Of The Year Award" twice for his contribution to education of radiology residents at New York Presbyterian Hospital, NY. He remains an active member of the radiology department as an Adjunct Professor of Radiology at Columbia University. He is certified by American Board of Radiology and holds Clinical Magnetic Resonance Society Certification in Body MRI, Orthopedic MRI and Neuroradiology MRI and also has a RPVI (Registered Physician Vascular Ultrasound Interpretaion) certification.  Dr. Milman is one of handful of NJ Radiologists who are recognized as Level III Coronary CTA certified and Cardiovascular CT board certified- the highest certification available in this field of cardiovascular imaging.

Awards and Recognition
Twice named "Teacher of the Year" New York Presbyterian Hospital 2012 Top Doc Award - NJ Monthly Magazine
Fred Berlin, M.D., RPVI
Vascular and Interventional Radiology

After finishing residency in Diagnostic Radiology at The Mount Sinai School of Medicine in New York, he then went on to receive subspecialty training during his clinical fellowship in Vascular and Interventional Radiology at The Mount Sinai Medical Center. Dr. Berlin has extensive experience and active interest in minimally invasive treatments for liver cancer including Yttrium-90 radioembolization, chemoembolization and thermal ablative therapies. He also focuses on minimally invasive treatments for uterine fibroids, peripheral arterial disease and complex venous revascularization, embolotherapy for hemorrhage and portal venous hypertension therapies such as Transjugular Intrahepatic Portosystemic Shunt (TIPS) and Balloon Occlusion Retrograde Transvenous Obliteration of Gastric Varices (BRTO). Additionally, Dr. Berlin has broad expertise in providing a wide variety of traditional Interventional Radiology procedures such as image guided biopsies, dialysis access, hepatobiliary, genitourinary and gastrointestinal interventions. Dr. Berlin was involved in numerous clinical trials, publications, abstracts and scientific exhibits and has been invited to lecture and present his clinical research in the field of minimally invasive interventions at multiple national conferences all over the country. He is board-certified by the American Board of Radiology in Diagnostic Radiology, is a member of American College of Radiology and Society of Interventional Radiology and has RPVI (Registered Physician Vascular Ultrasound Interpretation) certification.
Interventional Radiology
Interventional Radiology
Diagnostic Radiology

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Interventional Endoscopy

http://www.ganjllc.com/matthew-grossman.php

Training
Advanced Therapeutic Endoscopy Fellowship • Lennox Hill Hospital, New York, NY 2010

Gastroenterology Fellowship 2007-2010 • New York University Medical Center, NY, GI Division

Internal Medicine Internship and Residency • Columbia University Medical Center , New York, NY

UMDNJ Robert Wood Johnson Medical School - New Brunswick NJ • Doctor of Medicine • Alpha Omega Alpha Honors Society

Washington University - St. Louis, MO 1996-2000 • Bachelor of Science • Magnum Cum Laude • Major: Economics, Minor: Biology • Golden Key National Honors Society

Awards
GI fellow of the year 2008 - awarded for excellence in teaching house staff Dr. Howard J. Eddy Scholarship recipient 2008 for exceptional NYSGE GI Presentation NYSGE "fellows night" presentation winner - "Double Pylorus" Digestive Disease Week 2005 Poster of Distinction Alpha Omega Alpha Robert "Wood Johnson Dean's Academic' Scholarship Howard Hughes Summer Research Fellowship
Interventional Endoscopy
Director Gastroenterology Fellowship Program
St. Joseph's Medical Center

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Director of Tumor Board
St. Joseph's Medical Center
Director Medical Oncology Fellowship
St. Joseph's Medical Center

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